Anti-ELN antibodies are used in the immunodetection of the protein elastin. In humans, the canonical protein has a reported length of 786 amino acid residues and a mass of 68.4 kDa. Its subcellular localization is in the extracellular matrix and is secreted. Up to 13 different isoforms have been reported for this protein. It is noted to be expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus. A member of the Elastin protein family, ELN is known to be involved with organ morphogenesis and skeletal muscle tissue development. The ELN gene has been associated with the disease, Cutis laxa. Synonyms for this target antigen include SVAS, WBS, WS, tropoelastin, and ADCL1. ELN gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 90 citations in the literature describe the use of ELN antibodies in research. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.