Anti-CBS antibodies are used in the immunodetection of the protein cystathionine beta-synthase. In humans, the canonical protein has a reported length of 551 amino acid residues and a mass of 60.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the pancreas, liver, hippocampus, and cerebellum. A member of the Cysteine synthase/cystathionine beta-synthase protein family, CBS is known to be involved with the cellular response to hypoxia. Synonyms for this target antigen include HIP4, Cystathionine beta-synthase-like protein, beta-thionase, methylcysteine synthase, serine sulfhydrase, and CBSL. CBS gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Over 140 citations in the literature describe the use of CBS antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.