Anti-ULBP2 antibodies are used in the immunodetection of the protein UL16 binding protein 2. In humans, the canonical protein has a reported length of 246 amino acid residues and a mass of 27.4 kDa. Its subcellular localization is in the ER, cell membrane, and is secreted. It is reported to be expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. A member of the MHC class I protein family, ULBP2 is known to bind and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include NKG2D ligand 2 and retinoic acid early transcript 1H. Over 120 citations in the literature describe the use of ULBP2 antibodies in research. ELISA is a widely used application for these antibodies. In addition, Western Blot is also a common application.