Anti-ERBB antibodies are used in antigen-specific immunodetection in biological samples. The target ERBB is a known alias name of the protein epidermal growth factor receptor, encoded by the EGFR gene in humans. This 1210-amino acid residue protein is a known receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It is localized to the nucleus, ER, Golgi, and cell membrane of the cell and features methylated, glycosylated, ubiquitinated, palmitoylated and phosphorylated post-translational modifications. In terms of tissue expression, it is ubiquitously expressed across many tissue types. The term ERBB1 is another synonym for ERBB. Some ERBB antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.