Anti-CDSN antibodies are used in the immunodetection of the protein corneodesmosin. In humans, the canonical protein has a reported length of 529 amino acid residues and a mass of 51.5 kDa. It has been described to be a secreted protein. It is notably expressed in skin. CDSN is known to be important for the epidermal barrier integrity. Post-translational modifications have been described, including glycosylation. The CDSN gene has been associated with the disease, Hypotrichosis. Synonyms for this target antigen include HTSS1, HYPT2, PSS, PSS1, S protein, differentiated keratinocyte S protein, and HTSS. CDSN gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. A number of CDSN antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.