Anti-Plexin D1 antibodies are used in the immunodetection of the protein encoded by the PLXND1 gene. In humans, the canonical protein has a reported length of 1925 amino acid residues and a mass of 212 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Plexin protein family, it is a reported cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Post-translational modifications have been described, including glycosylation. Other names for this target antigen include CHTD9 and PLEXD1.