Anti-iron-sulfur cluster assembly factor IBA57 antibodies are used for the immunodetection of the protein encoded by the IBA57 gene. In humans, the canonical protein has a reported length of 356 amino acid residues and a mass of 38.2 kDa. Its subcellular localization is in the mitochondria. It is reported to be expressed in skin fibroblasts and skeletal muscle. A member of the GcvT protein family, it is reported to be involved in maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. The gene encoding this protein is implicated in Multiple mitochondrial dysfunctions syndrome. Other names for this target antigen include IBA57 homolog, iron-sulfur cluster assembly, IBA57, iron-sulfur cluster assembly homolog, and putative transferase CAF17, mitochondrial. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.