Anti-DOP1 leucine zipper like protein B antibodies are used for the immunodetection of the protein encoded by the DOP1B gene. In humans, the canonical protein has a reported length of 2298 amino acid residues and a mass of 258.2 kDa. Its subcellular localization is in the Golgi and membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the Dopey protein family, it is believed to play a role in regulating membrane trafficking of cargo proteins. Other names for this target antigen include C21orf5, DOPEY2, protein dopey-2, dopey family member 2, homolog of yeast DOP1, and 21orf5. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.