Anti-mitochondrial inner membrane protein MPV17 antibodies are used for the immunodetection of the protein encoded by the MPV17 gene. In humans, the canonical protein has a reported length of 176 amino acid residues and a mass of 19.7 kDa. Its subcellular localization is in the mitochondria. It is ubiquitously expressed across many tissue types. A member of the Peroxisomal membrane protein PXMP2/4 protein family, it is reported to be a non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. The gene encoding this protein is implicated in Mitochondrial DNA depletion syndrome. Other names for this target antigen include MTDPS6, SYM1, protein Mpv17, MPV17, mitochondrial inner membrane protein, MpV17 mitochondrial inner membrane protein, and CMT2EE. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chimpanzee species.