Anti-T-box transcription factor 18 antibodies are used for the immunodetection of the protein encoded by the TBX18 gene. In humans, the canonical protein has a reported length of 607 amino acid residues and a mass of 64.8 kDa. Its subcellular localization is in the nucleus. It is known to act as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. The gene encoding this protein is implicated in Congenital anomalies of kidney and urinary tract. Other names for this target antigen include PUJO, T-box transcription factor TBX18, T-box 18, T-box protein 18, and CAKUT2. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.