Anti-NBR1 autophagy cargo receptor antibodies are used for the immunodetection of the protein encoded by the NBR1 gene. In humans, the canonical protein has a reported length of 966 amino acid residues and a mass of 107.4 kDa. Its subcellular localization is in the cytoplasmic vesicles, lysosomes and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is noted to be involved in autophagy pathways and the regulation of cell differentiation. Post-translational modifications have been described, including ubiquitination, protein cleavage and phosphorylation. Other names for this target antigen include IAI3B, M17S2, MIG19, next to BRCA1 gene 1 protein, B-box protein, and 1A1-3B. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.