Anti-MAPK associated protein 1 antibodies are used for the immunodetection of the protein encoded by the MAPKAP1 gene. In humans, the canonical protein has a reported length of 522 amino acid residues and a mass of 59.1 kDa. Its subcellular localization is in the nucleus, cytoplasmic vesicles, and cell membrane. Alternative splicing is reported to yield 6 different isoforms for this protein. It is widely expressed across many tissue types. A member of the SIN1 protein family, it is known to be involved with cytoskeleton organization and the regulation of apoptosis. Other names for this target antigen include MEKK2-interacting protein 1, SAPK-interacting protein 1, TORC2 subunit MAPKAP1, mSIN1, and target of rapamycin complex 2 subunit MAPKAP1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.