Anti-ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase antibodies are used for the immunodetection of the protein encoded by the ALG1 gene. In humans, the canonical protein has a reported length of 464 amino acid residues and a mass of 52.5 kDa. Its subcellular localization is in the ER. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Glycosyltransferase group 1 protein family, it is known to catalyze the addition of the first of nine mannose moieties to form a dolichol-lipid linked oligosaccharide intermediate required for proper N-linked glycosylation. The gene encoding this protein is implicated in Congenital disorder of glycosylation. Other names for this target antigen include GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase, asparagine-linked glycosylation 1 homolog (yeast, beta-1,4-mannosyltransferase), and chitobiosyldiphosphodolichol beta-mannosyltransferase. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.