Anti-actin alpha cardiac muscle 1 antibodies are used for the immunodetection of the protein encoded by the ACTC1 gene. In humans, the canonical protein has a reported length of 377 amino acid residues and a mass of 42 kDa. Its subcellular localization is in the cytoplasm. A member of the Actin protein family, it is known to be involved with the regulation of apoptosis. Post-translational modifications have been described, including methylation, acetylation and protein cleavage. The gene encoding this protein is implicated in Cardiomyopathy. Other names for this target antigen include ASD5, CMD1R, CMH11, LVNC4, and ACTC. Gene orthologs have been identified in the mouse, rat, bovine, frog and chicken species.