Anti-FtsJ RNA 2'-O-methyltransferase 3 antibodies are used for the immunodetection of the protein encoded by the FTSJ3 gene. In humans, the canonical protein has a reported length of 847 amino acid residues and a mass of 96.6 kDa. Its subcellular localization is in the nucleus. A member of the RNA methyltransferase RlmE protein family, it is known to be a RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Other names for this target antigen include 2'-O-ribose RNA methyltransferase SPB1 homolog, FtsJ RNA methyltransferase homolog 3, FtsJ homolog 3, SPB1 RNA methyltransferase homolog, and pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.