Anti-protein tyrosine phosphatase non-receptor type 3 antibodies are used for the immunodetection of the protein encoded by the PTPN3 gene. In humans, the canonical protein has a reported length of 913 amino acid residues and a mass of 104 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of the Protein-tyrosine phosphatase protein family, it is believed to act at junctions between the membrane and the cytoskeleton. Other names for this target antigen include PTPH1, tyrosine-protein phosphatase non-receptor type 3, cytoskeletal-associated protein tyrosine phosphatase, protein-tyrosine phosphatase H1, and PTP-H1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.