Anti-small ubiquitin like modifier 2 antibodies are used for the immunodetection of the protein encoded by the SUMO2 gene. In humans, the canonical protein has a reported length of 95 amino acid residues and a mass of 10.9 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 2 different isoforms for this protein. It is widely expressed across many tissue types. A member of the Ubiquitin protein family, it is reported to be a ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Post-translational modifications have been described, including ubiquitination and protein cleavage. Other names for this target antigen include SMT3B, SMT3H2, SUMO3, Smt3A, small ubiquitin-related modifier 2, and HSMT3. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.