Anti-MAPK interacting serine/threonine kinase 1 antibodies are used for the immunodetection of the protein encoded by the MKNK1 gene. In humans, the canonical protein has a reported length of 465 amino acid residues and a mass of 51.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 3 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of the CAMK Ser/Thr protein kinase protein family, it is believed to play a role in the response to environmental stress and cytokines. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include MAP kinase-interacting serine/threonine-protein kinase 1, MAP kinase interacting serine/threonine kinase 1, MAP kinase signal-integrating kinase 1, MAPK signal-integrating kinase 1, and MNK1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.