Anti-guided entry of tail-anchored proteins factor 1 antibodies are used for the immunodetection of the protein encoded by the GET1 gene. In humans, the canonical protein has a reported length of 174 amino acid residues and a mass of 19.8 kDa. Its subcellular localization is in the ER. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the WRB/GET1 protein family, it is known to be required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum (ER). Other names for this target antigen include WRB, congenital heart disease 5 protein, tail-anchored protein insertion receptor WRB, tryptophan rich basic protein, and CHD5. Gene orthologs have been identified in the mouse, rat, chimpanzee and chicken species.