Anti-small ubiquitin like modifier 3 antibodies are used for the immunodetection of the protein encoded by the SUMO3 gene. In humans, the canonical protein has a reported length of 103 amino acid residues and a mass of 11.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be highly expressed in the liver. A member of the Ubiquitin protein family, it is reported to be a ubiquitin-like protein, which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Post-translational modifications have been described, including protein cleavage. Other names for this target antigen include SMT3H1, Smt3B, small ubiquitin-related modifier 3, SMT3 suppressor of mif two 3 homolog 1, SMT3 suppressor of mif two 3 homolog 3, and SMT3A. Gene orthologs have been identified in the mouse, rat, bovine, frog and chimpanzee species.