Anti-small ubiquitin like modifier 4 antibodies are used for the immunodetection of the protein encoded by the SUMO4 gene. In humans, the canonical protein has a reported length of 95 amino acid residues and a mass of 10.7 kDa. It is notably expressed in adult and embryonic kidney. A member of the Ubiquitin protein family, it is reported to be a ubiquitin-like protein, which can be covalently attached to target lysines as a monomer. The gene encoding this protein is implicated in Type 1 diabetes mellitus. Other names for this target antigen include SMT3 suppressor of mif two 3 homolog 2, SMT3 suppressor of mif two 3 homolog 4, insulin-dependent diabetes mellitus 5, small ubiquitin-like modifier 4 protein, and small ubiquitin-related modifier 4. Gene orthologs have been identified in the mouse, rat and chimpanzee species.