Anti-oxoglutarate dehydrogenase L antibodies are used for the immunodetection of the protein encoded by the OGDHL gene. In humans, the canonical protein has a reported length of 1010 amino acid residues and a mass of 114.5 kDa. Its subcellular localization is in the mitochondria. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be expressed in the brain and the liver. A member of the Alpha-ketoglutarate dehydrogenase protein family, it is known to be involved with metabolic processes. The gene encoding this protein is implicated in Yoon-Bellen neurodevelopmental syndrome. Other names for this target antigen include 2-oxoglutarate dehydrogenase complex component E1-like, OGDC-E1-like, alpha-ketoglutarate dehydrogenase-like, oxoglutarate dehydrogenase like, and 2-oxoglutarate dehydrogenase-like, mitochondrial. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.