Anti-MARCHF1 antibodies are used in the immunodetection of the protein membrane associated ring-CH-type finger 1. In humans, the canonical protein has a reported length of 289 amino acid residues and a mass of 32.3 kDa. Its subcellular localization is in the cytoplasmic vesicles, Golgi, lysosomes, and cell membrane. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in antigen presenting cells, APCs, located in lymph nodes and spleen. MARCHF1 is known to be involved with immune response pathways and protein ubiquitination. Synonyms for this target antigen include RNF171, E3 ubiquitin-protein ligase MARCHF1, E3 ubiquitin-protein ligase MARCH1, RING finger protein 171, and MARCH-I. MARCHF1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.