Anti-COL25A1 antibodies are used in the immunodetection of the protein collagen type XXV alpha 1 chain. In humans, the canonical protein has a reported length of 654 amino acid residues and a mass of 64.8 kDa. Its subcellular localization is in the membrane. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in the brain. COL25A1 is reported to inhibit fibrillization of amyloid-beta peptide during the elongation phase. Post-translational modifications have been described, including glycosylation and protein cleavage. The COL25A1 gene has been associated with the disease, Fibrosis of extraocular muscles. Synonyms for this target antigen include alzheimer disease amyloid-associated protein, collagen-like Alzheimer amyloid plaque component, collagenous Alzheimer amyloid plaque component, and collagen alpha-1(XXV) chain. COL25A1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some COL25A1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.