Anti-thioredoxin-related transmembrane protein 3 antibodies enable researchers to detect and measure the thioredoxin-related transmembrane protein 3 antigen in biological samples. This target is a reported synonym of the TMX3 gene, which encodes thioredoxin related transmembrane protein 3. This protein is a suspected disulfide isomerase, which participates in the folding of proteins containing disulfide bonds. The human version of thioredoxin-related transmembrane protein 3 has a canonical amino acid length of 454 residues and a protein mass of 51.9 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the ER of cells. thioredoxin-related transmembrane protein 3 is a member of the Protein disulfide isomerase protein family.