Anti-selenoprotein K antibodies are used in the immunodetection of the protein encoded by the SELENOK gene. In humans, the canonical protein has a reported length of 94 amino acid residues and a mass of 10.6 kDa. Its subcellular localization is in the ER and cell membrane. It is reported to be highly expressed in heart. A member of the Selenoprotein K protein family, it is known to be required for Ca(2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration (By similarity). Post-translational modifications have been described, including ubiquitination and protein cleavage.