Anti-SMARCD2 antibodies are used in the immunodetection of the protein SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. In humans, the canonical protein has a reported length of 531 amino acid residues and a mass of 58.9 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 3 different isoforms for this protein. A member of a the SMARCD protein family, SMARCD2 is known to be involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Post-translational modifications have been described, including ubiquitination. Synonyms for this target antigen include CRACD2, PRO2451, Rsc6p, SGD2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2, and BAF60B.