Anti-MACC1 antibodies are used in the immunodetection of the protein MET transcriptional regulator MACC1. In humans, the canonical protein has a reported length of 852 amino acid residues and a mass of 96.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is found to be highly expressed in metastasizing tumors. MACC1 is known to act as a transcription activator for MET and as a key regulator of HGF-MET signaling. Synonyms for this target antigen include MACC1, MET transcriptional regulator, SH3 domain-containing protein 7a5, metastasis associated in colon cancer 1, putative binding protein 7a5, and metastasis-associated in colon cancer protein 1. MACC1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 60 citations in the literature describe the use of MACC1 antibodies in research. Immunohistochemistry is a widely used application for these antibodies. ELISA, Western Blot, and Immunofluorescence are also common applications.