Anti-MAF antibodies are used in the immunodetection of the protein MAF bZIP transcription factor. In humans, the canonical protein has a reported length of 373 amino acid residues and a mass of 38.5 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in endothelial cells. A member of the BZIP protein family, MAF is known to act as a transcriptional activator or repressor. Post-translational modifications have been described, including ubiquitination and phosphorylation. The MAF marker can be used to identify Gray Matter MGE Interneurons, T Follicular Helper Cells, and Dorsal Excitatory Neurons.* Synonyms for this target antigen include CCA4, CTRCT21, c-MAF, transcription factor Maf, Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene, and AYGRP. MAF gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4