Anti-GLIPR1 like 1 antibodies are used in the immunodetection of the protein encoded by the GLIPR1L1 gene. In humans, the canonical protein has a reported length of 242 amino acid residues and a mass of 27.2 kDa. Its subcellular localization is in the cytoplasmic vesicles, cell membrane, and is also secreted. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be highly expressed in testis. A member of the CRISP protein family, it is known to be required for optimal fertilization at the stage of sperm-oocyte fusion, plays a role in optimizing acrosome function, the translocation of IZUMO1 during the acrosome reaction and the fertilization process. Post-translational modifications have been described, including N-glycosylation. Other names for this target antigen include GLIPR1-like protein 1 and GLI pathogenesis related 1 like 1.