Anti-CCBE1 antibodies are used in the immunodetection of the protein collagen and calcium binding EGF domains 1. In humans, the canonical protein has a reported length of 406 amino acid residues and a mass of 44.1 kDa. It has been described to be a secreted protein. Up to 3 different isoforms have been reported for this protein. It is notably expressed in fibroblasts and urine. A member of the CCBE1 protein family, CCBE1 is known to be required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Post-translational modifications have been described, including glycosylation.
The CCBE1 marker can be used to identify Amygdala Excitatory Neurons, Hippocampal Gyrus CA1-3 Neurons, and Gray Matter Neurons.* Synonyms for this target antigen include collagen and calcium-binding EGF domain-containing protein 1 and full of fluid protein homolog. CCBE1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some CCBE1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4