Anti-TWIST2 antibodies are used in the immunodetection of the protein twist family bHLH transcription factor 2. In humans, the canonical protein has a reported length of 160 amino acid residues and a mass of 18.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. TWIST2 is known to bind to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. The TWIST2 gene has been associated with the disease, Focal facial dermal dysplasia. Synonyms for this target antigen include class A basic helix-loop-helix protein 39, dermis-expressed protein 1, twist basic helix-loop-helix transcription factor 2, twist homolog 2, twist-related bHLH protein Dermo1, and twist-related protein 2. TWIST2 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of Twist2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.