Anti-FRMPD2 antibodies are used in the immunodetection of the protein FERM and PDZ domain containing 2. In humans, the canonical protein has a reported length of 1309 amino acid residues and a mass of 144.3 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is reported to be expressed in epithelial cells. FRMPD2 is believed to play a role in the regulation of tight junction formation. The FRMPD2 marker can be used to identify Hypothalamus Mammillary Body Neurons.* Synonyms for this target antigen include PDZ domain containing 5C, PDZ domain-containing protein 4, and FERM and PDZ domain-containing protein 2. FRMPD2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish and chimpanzee species. Immunohistochemistry is the most common application for the FRMPD2 antibodies listed below. ELISA and Western Blot are also common applications.
*HuBMAP Human Reference Atlas v1.4