Anti-PROC antibodies are used in the immunodetection of the protein protein C, inactivator of coagulation factors Va and VIIIa. In humans, the canonical protein has a reported length of 461 amino acid residues and a mass of 52.1 kDa. Its subcellular localization is in the ER, Golgi, and is secreted. Up to 2 different isoforms have been reported for this protein. A member of the Peptidase S1 protein family, PROC is known to be involved with the regulation of apoptosis and proteolysis. Post-translational modifications have been described, including O-glycosylation, N-glycosylation and phosphorylation. Synonyms for this target antigen include PC, PROC1, THPH3, THPH4, vitamin K-dependent protein C, Protein C-Nagoya, activated protein C, and APC. PROC gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of PROC antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.