Anti-GPC5 antibodies are used in the immunodetection of the protein glypican 5. In humans, the canonical protein has a reported length of 572 amino acid residues and a mass of 63.7 kDa. Its subcellular localization is in the cell membrane. It is notably widely expressed in many tissue types. A member of the Glypican protein family, GPC5 is known to be involved with cell migration and the Wnt signaling pathway. Post-translational modifications have been described, including glycosylation. The GPC5 marker can be used to identify Brain Astrocytes.* Synonyms for this target antigen include bA93M14.1 and glypican proteoglycan 5. GPC5 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of Gpc5 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.
*HuBMAP Human Reference Atlas v1.4