Anti-HUS1 antibodies are used in the immunodetection of the protein HUS1 checkpoint clamp component. In humans, the canonical protein has a reported length of 280 amino acid residues and a mass of 31.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is ubiquitously expressed across many tissue types. A member of a the HUS1 protein family, HUS1 is a known component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. Synonyms for this target antigen include checkpoint protein HUS1, HUS1 checkpoint homolog, hus1+-like protein, and hHUS1.