Anti-CGI-50 antibodies are protein reagents that detect specific antigens. The CGI-50 antigen is another term for the human protein WD repeat domain, phosphoinositide interacting 2, encoded by the WIPI2 gene. The protein is a known component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Canonically, it has an amino acid length of 454 residues and a mass of 49.4 kilodaltons. Its subcellular localization is in the membrane and it is ubiquitously expressed across many tissue types. The CGI-50 protein is a member of the WD repeat PROPPIN protein family. Other alias names for CGI-50 include ATG18B, Atg21, and CGI-50.