Anti-GID2 antibodies enable researchers to detect and measure the GID2 antigen in biological samples. This target is a reported synonym of the RMND5B gene, which encodes required for meiotic nuclear division 5 homolog B. This protein is an important component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. The human version of GID2 has a canonical amino acid length of 393 residues and a protein mass of 44.4 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the cytoplasm of cells.