C.BIRD in Studying Programmed Cell Death

Budapest University of Technology and Economics

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Performance

Ease-of-Optimization

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Company:

CYTENA

Product Name:

C.BIRD™ Microbioreactor

Catalog Number:

D16110023454

The main focus of our laboratory is to study programmed cell death and the effects of various media additives on different cell lines. Thus, we aim to test multiple molecules in multiple concentrations and combinations, so we must work on 96/24-well plates.However, we faced some difficulties in the case of suspension cell lines. In the case of regular 96/24-well plates, we experienced severe media evaporation and cell sedimentation at the bottom of the wells due to inadequate mixing. C.BIRD helped us overcome these problems by sufficiently mixing the cells and preventing media evaporation.

Experimental Design and Results Summary

Application

Incubating mAb-producing CHO DG44 cells treated with various media additives for later analysis.

Tips

The moats of the plates should be filled with distilled water before putting them into C.BIRD.

DOI or PMID #

N/A

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Summary

The Good

Prevents media evaporation, mixes the cells to prevent cell sedimentation in the well, 3 96/24-well plates can be put into C.BIRD at the same time, easy-to-use software.

The Bad

The instrument has to be connected to a PC continuously (no built-in memory).

The Bottom Line

Really great equipment to test the effect of various media additives fast and reliably.

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