Nice DiR Near Infrared Dye Fluorescent Labeling Agent

Houston Methodist Research Institute
Nanomedicine
Postdoctoral Researcher

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
Write a Review

Company:

Invitrogen™

Product Name:

DiR'; DiIC18(7) (1,1'-Dioctadecyl-3,3,3',3'-Tetramethylindotricarbocyanine Iodide)

Catalog Number:

D12731

Our research goal is to track the biodistribution of the exosome. We used DiR to stain the exosome as DiR is lipophilic and can incorporate into membranes. DiR-labelled exosomes were injected via tail vein. The 750 nm channel was used to excite DiR, and emission was observed at 800 nm.

Experimental Design and Results Summary

Application

Cell membrane labeling and in vivo imaging

Starting Material

N/A

Tips

Protect from light.

Results Summary

We detected the DiR-labelled exosome using a Small Animal Imaging System. The signal looked great because of the effective transmission of infrared light through cells and tissues and the low level of autofluorescence in the infrared range.

DOI or PMID #

N/A

Image Gallery

Summary

The Good

Good signal.

The Bad

Little expensive.

The Bottom Line

Has great signal for in vivo imaging. Would buy it again.

Join the discussion