Tocris Bioscience
T 0070907
2301/5
Info:Supplier Page View Product Specs View Product
HL-1 cardiomyocytes were incubated with T 0070907 (1 µM) for 30 min prior to addition of 15 µM 15d-PGJ2 for 30 min. Preincubation of cells with T 0070907 completely abolished activation of p42/44 MAPK indicating involvement of PPAR gamma in cellular signaling in response to 15d-PGJ2.
Cell culture
N/A
HL-1 cardiomyocytes were incubated with T 0070907 (1 µM) for 30 min prior to addition of 15 µM 15d-PGJ2 for 30 min.
Preincubation of cells with T 0070907 completely abolished activation of p42/44 MAPK indicating involvement of PPAR gamma in cellular signaling in response to 15d-PGJ2.
Works as expected
T 0070907 inhibits 15d-PGJ2-induced ERK activation in cardiomyocytes.