Tocris Bioscience
R 7050
5432/10
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HL-1 cells were incubated with R 7050 (30 μM) for 30 min prior to 15d-PGJ2 (15 μM) treatments for 4 hr to follow markers of apoptosis. Pharmacological antagonism of TNF receptor inhibited 15d-PGJ2-induced caspase 3/8/9 activation (shown in Image).
Cell culture
N/A
HL-1 cells were incubated with R 7050 (30 μM) for 30 min prior to 15d-PGJ2 (15 μM) treatments for 4 hr to follow markers of apoptosis.
NA
Pharmacological antagonism of TNF receptor inhibited 15d-PGJ2-induced caspase 3/8/9 activation (shown in Image).
Works as expected
R 7050 inhibits 15d-PGJ2 induced caspase activation