Tocris Bioscience
Ivabradine hydrochloride
6542/10
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Primary human atrial cardiomyocytes were patched to analyze mean current–voltage relationships of pacemaker current (If) before and after ivabradine superfusion (1 μmol/L, 7 min). Ivabradine significantly reduced pacemaker current density (pA/pF) from − 80 to − 130 mV (shown in Image).
Cardiac electrophysiology
N/A
Primary human atrial cardiomyocytes were patched to analyze mean current–voltage relationships of pacemaker current (If) before and after ivabradine superfusion (1 μmol/L, 7 min).
Ivabradine significantly reduced pacemaker current density (pA/pF) from − 80 to − 130 mV (shown in Image).
Works as expected
Effect of ivabradine on pacemaker of human atrial myocytes