Nifedipine Blocks L-Type Ca2+ Current In Primary Cardiomyoytes

February 15, 2019

Medical University of Graz
Department of Cardiology
Postdoctoral Researcher

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Company:

Tocris Bioscience

Product Name:

Nifedipine

Catalog Number:

1075/100

L-type Ca2+ current of guinea pig cardiomyocytes before and after nifedipine (1 µM) superfusion for 5 min. Compared to time-matched rundown, nifedipine significantly blocked L-type Ca2+ current in cardiomyocytes.

Experimental Design and Results Summary

Application

Cardiac electrophysiology

Starting Material

Guinea pig cardiomyocytes

Protocol Overview

L-type Ca2+ current of guinea pig cardiomyocytes before and after nifedipine (1 µM) superfusion for 5 min.

Tips

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Results Summary

Compared to time-matched rundown, nifedipine significantly blocked L-type Ca2+ current in cardiomyocytes.

DOI or PMID #

N/A

Additional Notes

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The Bottom Line

Compared to time-matched rundown, nifedipine significantly blocked L-type Ca2+ current in cardiomyocytes.

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