Amlodipin Blocks Cardiac Calcium Current

February 13, 2019

Medical University of Graz
Department of Cardiology
Postdoctoral Researcher

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Company:

Tocris Bioscience

Product Name:

Amlodipine besylate

Catalog Number:

2571/50

L-type Ca2+ current was analysed by patch clamp in guinea pig ventricular cardiomyocytes before and after amlodipine (10 µM) superfusion. Amlodipine blocked calcium current density.

Experimental Design and Results Summary

Application

Electrophysiology

Starting Material

Guinea pig ventricular cardiomyocytes

Protocol Overview

Amlodipine was dissolved in Tyrode solution at a concentration of 10 µM.

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Results Summary

Amlodipine blocked calcium current density.

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The Bottom Line

Amlodipine blocks calcium current density in cardiomyocytes.

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