Clean and Consistent Lipid Product

November 11, 2016

University of Michigan
Pharmaceutical Sciences
Research Fellow

Overall

Quality of Results

Ease-of-Optimization

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Company:

Avanti Polar Lipids

Product Name:

16:0 PC (DPPC)

Catalog Number:

850355

For a pharmaceutical formulation project, there was a need to obtain consistent liposomes of DPPC. We bought and utilized DPPC from Avanti and synthesized liposomes of consistent size and character using the conventional thin film hydration technique as noted from the figure.

Experimental Design and Results Summary

Application

Pharmaceutical Formulation

Starting Material

DPPC (dipalmitoylphosphatidylcholine)

Protocol Overview

Conventional thin-film hydration technique was used to prepare liposomes of this lipid.

Tips

No special instructions or tips. Use the dry powder fresh for best results (do not store organic solvent based stocks for more than 2 months).

Results Summary

As noted from the figure obtained from Transmission Electron Microscopy, really consistent liposomes could be prepared.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

Cheap, reliable source of DPPC for characterizing and producing multiple batches for trials

The Bad

None. Follow the instructions for storage

The Bottom Line

Great, inexpensive product. Easy to use and store. Consistency in producing liposomes.

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