Fantastic for measuring epithelial barrier function

Northwestern University
Medicine, Division of Allergy-Immunology
Graduate Student

Overall

Performance

Ease-of-Optimization

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Company:

World Precision Instruments

Product Name:

EVOM2, Epithelial Voltohmmeter for TEER

Catalog Number:

EVOM2

I got this voltmeter about 3 years ago, and it still works great. I measure barrier function of human airway epithelial cells cultured at air liquid interface. It gives me reliable data, and it doesn't need to be charged very often. Results were published in J Allergy Clin Immunololgy: Oncostatin M promotes mucosal epithelial barrier dysfunction, and its expression is increased in patients with eosinophilic mucosal disease., Pothoven KL, Norton JE, Hulse KE, Suh LA, Carter RG, Rocci E, Harris KE, Shintani-Smith S, Conley DB, Chandra RK, Liu MC, Kato A, Gonsalves N, Grammer LC 3rd, Peters AT, Kern RC, Bryce PJ, Tan BK, Schleimer RP., J Allergy Clin Immunol. 2015 Apr 1. pii: S0091-6749(15)00188-8. doi: 10.1016/j.jaci.2015.01.043. [Epub ahead of print]

Experimental Design and Results Summary

Application

Assessment of epithelial barrier function

Starting Material

Differentiated airway epithelium

Protocol Overview

1: Sterilize the probe 2: measure the resistance of the epithelial cells

Tips

None, it's really easy to use

Results Summary

I get reliable data of epithelial barrier function

Features Summary

NA

Additional Notes

None

Image Gallery

Summary

The Good

Works great

The Bad

None

The Bottom Line

Works great

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