The Good
Obtained good results; confirmed proposed protein-RNA interaction
The Bad
Kit only comes with enough material for 12 reactions, and a lot of antibody is needed, so this experiment tends to be a little pricy
The Bottom Line
Don't skimp on reagents, use plenty of starting material, and make sure your antibody is good for IP reactions. A little pricy, but fairly easy to use and gives you solid data. Definitely worth it.