Automated Immunostainers

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DISCOVERY - Automated IHC/ISH Staining Solutions for Research

Ventana Medical Systems, Inc.

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PPOH

Cayman Chemical

Catalog Number: 75760
Description: Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, ω-1 and ω-hydroxylated compounds via what is known as the epoxidase pathway. PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. PPOH inhibits the formation of arachidonate 11,12 epoxides by CYP4A2 and CYP4A3 enzymes with an IC50 of 9 µM, but has effect on the formation of 20-HETE, the ω-hydroxylation product of CYP4A1.

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DISCOVERY ULTRA

Ventana Medical Systems, Inc.

Catalog Number: 750-601
Description: The Ventana DISCOVERY ULTRA instrument is the solution for scientists and research professionals who demand more than conventional immunohistochemistry (IHC) and in situ hybridization (ISH) research methods offer. No other fully automated IHC/ISH system offers the freedom and flexibility of DISCOVERY ULTRA. DISCOVERY ULTRA offers: Flexibility - Unmatched protocol flexibility for rapid assay development. Enhanced multiplexing and immunofluorescence. Run 30 completely independent protocols for improved workflow. Reproducibility - Fully automated slide processing, baking through staining. Ready-to-use optimized reagents. Apply precise heating to each slide individually for greater control over IHC/ISH reactions. Reagent choice -Choose your own antibodies, probes, pretreatments, fluorescence, linkers and blockers. Select the detection chemistry that best meets your needs.

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Discovery Ultra

Ventana Medical Systems, Inc.

Catalog Number: 750-601
Description: The Ventana DISCOVERY ULTRA instrument is the solution for scientists and research professionals who demand more than conventional immunohistochemistry (IHC) and in situ hybridization (ISH) research methods offer. No other fully automated IHC/ISH system offers the freedom and flexibility of DISCOVERY ULTRA. DISCOVERY ULTRA offers: Flexibility - Unmatched protocol flexibility for rapid assay development. Enhanced multiplexing and immunofluorescence. Run 30 completely independent protocols for improved workflow. Reproducibility - Fully automated slide processing, baking through staining. Ready-to-use optimized reagents. Apply precise heating to each slide individually for greater control over IHC/ISH reactions. Reagent choice -Choose your own antibodies, probes, pretreatments, fluorescence, linkers and blockers. Select the detection chemistry that best meets your needs.

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Discovery XT

Ventana Medical Systems, Inc.

Catalog Number: 750-701
Description: Platform Overview The DISCOVERY XT biomarker platform brings unprecedented automation, reproducibility, and productivity to immunohistochemisty (IHC) and in situ hybridization (ISH) slide preparation and processing. The flexible platform and sophisticated detection and reagent systems will help you to accelerate the discovery of new targets, biomarkers, speed assay development, and target validation while quickly determining the toxicity of new drug candidates in the preclinical phase. The DISCOVERY XT biomarker platform holds over ninety patented technologies — automation by innovators, for innovators. Structure The DISCOVERY XT biomarker platform can be divided into three main modules: Staining Automated fluidics Waste Each module works flawlessly together with the others to automate all slide processing steps—from baking through staining. The seamless integration of each module in this system allows for increased thoughput with rapid turnaround times. Each module maintains individual functionality while being commanded from a single center. This ease of automation grants walk-away convenience and operational simplicity. Modules The staining module creates an optimized environment for the automated preparation and processing of IHC, ISH, FISH, tissue, and DNA microarray applications. The automated fluidics module houses bulk solutions that are specifically formulated to enhance the kinetics and reproducibility of automated applications with the onboard bulk fluid capacity to process up to 90 slides. The waste module consists of two easy-empty containers with independent level sensing which has a capacity for walkaway operation.

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Discovery XT

Ventana Medical Systems, Inc.

Catalog Number: 750-701
Description: Platform Overview The DISCOVERY XT biomarker platform brings unprecedented automation, reproducibility, and productivity to immunohistochemisty (IHC) and in situ hybridization (ISH) slide preparation and processing. The flexible platform and sophisticated detection and reagent systems will help you to accelerate the discovery of new targets, biomarkers, speed assay development, and target validation while quickly determining the toxicity of new drug candidates in the preclinical phase. The DISCOVERY XT biomarker platform holds over ninety patented technologies — automation by innovators, for innovators. Structure The DISCOVERY XT biomarker platform can be divided into three main modules: Staining Automated fluidics Waste Each module works flawlessly together with the others to automate all slide processing steps—from baking through staining. The seamless integration of each module in this system allows for increased thoughput with rapid turnaround times. Each module maintains individual functionality while being commanded from a single center. This ease of automation grants walk-away convenience and operational simplicity. Modules The staining module creates an optimized environment for the automated preparation and processing of IHC, ISH, FISH, tissue, and DNA microarray applications. The automated fluidics module houses bulk solutions that are specifically formulated to enhance the kinetics and reproducibility of automated applications with the onboard bulk fluid capacity to process up to 90 slides. The waste module consists of two easy-empty containers with independent level sensing which has a capacity for walkaway operation.

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