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TUNEL Assays for Apoptosis
Thursday, April 10, 2014
One established hallmark of apoptosis is DNA fragmentation, commonly measured using the terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick...
High-Content Screening Systems
Thursday, March 13, 2014
Today’s high-content screening systems are faster, more flexible, and more sensitive than ever. But not all systems are alike, and each has its pros ...
Motion Tracking in Live-Cell Imaging
Thursday, February 20, 2014
An important facet of live-cell imaging is motion tracking—using microscopes and software to follow the position of cells or subcellular structures as...
Label-Free Cell Analysis
Tuesday, January 14, 2014
Cell biology with neither labels nor molecular tags may puzzle researchers learned in fluorophores and fluorescent proteins, but that doesn't mean you...
The Latest in Live Cell Imaging
Friday, February 22, 2013
We want to elucidate the dynamic events that go on inside cells. What are proteins doing and what are their interactions? With live-cell imaging, ...
Consider Camera, Stage Height, and More When Purchasing an Inverted Microscope
Tuesday, January 15, 2013
Purchasing such an inverted microscope can be a huge investment for a laboratory, especially a small one. It’s important to consider the price of the ...
Laser Capture Microdissection
Monday, July 02, 2012
Eukaryotic tissue is, as we all know, not homogenous. It is built of different cell types, with distinct functions, morphologies and gene expression ...
Tuesday, May 15, 2012
Although microscopists routinely generate beautiful, clear images, those images still suffer from one significant limitation: the diffraction limit. A...
Microscopy for Non-microscopists
Wednesday, January 11, 2012
The eukaryotic cell has never looked so good. From the pages of scientific journals to the covers of biology textbooks, cells are being captured at ...
Live Cell Imaging
Wednesday, October 13, 2010
Imagine you want to understand the rules of American football. If a friend showed you three snapshots taken during one game, would you be able to suss...
Monday, February 15, 2010
The power to see inside cells, inside organelles, even to see individual molecules, is growing at an alarming rate. Cellular imaging is changing ...
Single Cell Technologies
Wednesday, January 13, 2010
Gene expression studies have deepened our understanding of important cellular functions. However, they often assume that cells of a particular type ...
Imaging And Microscopy: Seeing More, More Easily
Monday, June 15, 2009
Whether you’re a professional microscopist or once did an imaging rotation in graduate school – and then resolved never again – our ability to see ...
P53/ATM Aquarius Hematology FISH Probe
I am investigating chromosomal aberrations in lymphoma and have used the P53/ATM probe to assess gain and loss of these targets from fresh-frozen imprint slides...
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