Editorial Articles

  • Microscopy: Live and in Color (or More Likely, Monochrome)

    Live-Cell Imaging

    Thursday, March 12, 2015
    If you want to do live-cell imaging yourself, you’ll need more than just a microscope. Additional enabling equipment is usually required to keep the ... read more
  • Average, Shmaverage! Embrace Heterogenity with Single-Cell Transcriptomics

    Single-Cell Transcriptomics

    Friday, January 23, 2015
    Researchers have over the past few years developed tools to downsize their research to the single-cell level. Some are based on next-generation DNA ... read more
  • See Neurons Clearly with CLARITY

    CLARITY Neuroimaging

    Tuesday, December 16, 2014
    Researchers have devised strategies to make brains optically transparent, thereby obviating the need for thin tissue sectioning. One, published in ... read more
  • Ten Mobile Apps for Biology Laboratories

    Mobile Apps for the Lab

    Wednesday, October 29, 2014
    As in so many facets of society, smartphones and tablets are transforming the research laboratory. We offer a handful of useful options for today’s ... read more
  • Look Beneath the Surface with Two-Photon Microscopy

    Two-Photon Microscopy

    Friday, October 17, 2014
    It can be tough to get a clear microscope image through more than a single layer of cells. All that extra material scatters and absorbs light, a ... read more
  • Take Sharp Pictures Fast with Live-Cell Super-Resolution Microscopy

    Live-Cell Super-Resolution Microscopy

    Tuesday, August 05, 2014
    Super-resolution microscopy gives microscopists the ability to see past the diffraction limit, and researchers have used it to produce some stunning ... read more
  • Take Your Genomics to the Single-Cell Level with These Cell Isolation Techniques

    Isolation Techniques for Single-Cell Genomics

    Thursday, July 31, 2014
    Single-cell genomics is exactly what it sounds like: Researchers isolate individual cells, lyse them and amplify and sequence their genomic DNA. The ... read more
  • Watch Cells Die with These TUNEL Assay Kits

    TUNEL Assays for Apoptosis

    Thursday, April 10, 2014
    One established hallmark of apoptosis is DNA fragmentation, commonly measured using the terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick... read more
  • Spy on Your Cells With These High-Content Screening Systems

    High-Content Screening Systems

    Thursday, March 13, 2014
    Today’s high-content screening systems are faster, more flexible, and more sensitive than ever. But not all systems are alike, and each has its pros ... read more
  • Motion Tracking in Live-Cell Imaging

    Motion Tracking in Live-Cell Imaging

    Thursday, February 20, 2014
    An important facet of live-cell imaging is motion tracking—using microscopes and software to follow the position of cells or subcellular structures as... read more
  • Study Your Cells sans Fluorophores with these Label-Free Analysis Systems

    Label-Free Cell Analysis

    Tuesday, January 14, 2014
    Cell biology with neither labels nor molecular tags may puzzle researchers learned in fluorophores and fluorescent proteins, but that doesn't mean you... read more
  • What's Going on in There?  See It All With Live Cell Imaging

    The Latest in Live Cell Imaging

    Friday, February 22, 2013
    We want to elucidate the dynamic events that go on inside cells. What are proteins doing and what are their interactions? With live-cell imaging, ... read more
  • Consider Camera, Stage Height, and More When Purchasing an Inverted Microscope

    Consider Camera, Stage Height, and More When Purchasing an Inverted Microscope

    Tuesday, January 15, 2013
    Purchasing such an inverted microscope can be a huge investment for a laboratory, especially a small one. It’s important to consider the price of the ... read more
  • Laser Capture Microdissection (LCM): The First Step in Single Cell Analysis

    Laser Capture Microdissection

    Monday, July 02, 2012
    Eukaryotic tissue is, as we all know, not homogenous. It is built of different cell types, with distinct functions, morphologies and gene expression ... read more
  • Super Clear Images with Super-resolution Microscopy

    Super-resolution Microscopy

    Tuesday, May 15, 2012
    Although microscopists routinely generate beautiful, clear images, those images still suffer from one significant limitation: the diffraction limit. A... read more
  • Microscopy for Non-microscopists

    Microscopy for Non-microscopists

    Wednesday, January 11, 2012
    The eukaryotic cell has never looked so good. From the pages of scientific journals to the covers of biology textbooks, cells are being captured at ... read more